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Symbol
Name
ID
Wnt4
wingless-type MMTV integration site family, member 4
MGI:98957
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Increased circulating androstenedione concentration
Increased circulating dehydroepiandrosterone-sulfate concentration
Increased serum testosterone level
Disease(s) Associated with WNT4
Mullerian aplasia and hyperandrogenism

Mouse Phenotypes
abnormal adenohypophysis morphology
decreased gonadotroph cell number
decreased somatotroph cell number
decreased thyrotroph cell number
decreased thymocyte number
abnormal ovary morphology
decreased mature ovarian follicle number
absent ovary capsule
abnormal ovary development
decreased ovary weight
abnormal adrenal gland physiology
Availability Mouse Genotype
Wnt4tm1Amc/Wnt4tm1Amc
Amhr2tm3(cre)Bhr/Amhr2+
Wnt4tm1.1Boer/Wnt4tm1.2Boer  (conditional)
Wnt4tm2(EGFP/cre)Svo/Wnt4tm1Svo  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory